Assessment of Serum and Salivary levels of Synuclein-γ as a Diagnostic Biomarker in Oral Squamous Cell Carcinoma Patients

Authors

Aya Yasser, Clinical demonstrator, Department of Oral Medicine, Periodontology, Diagnosis and oral Radiology, Faculty of Dentistry, Mansoura University, EgyptFollow
Shadi Awny, Assistant professor, Oncology Center, Mansoura University, Egypt
Shaimaa R. Hendawy, Assistant Professor, Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Egypt
Mohamed M. Anees, Professor, Department of Oral Medicine, Periodontology, Diagnosis and Oral Radiology, Faculty of Dentistry, Mansoura University, Egypt

Article Type

Original Article

Section/Category

Oral Medicine

Abstract

Objective: The objective of the current study was to assess the serum and salivary levels of Synuclein-γ (SNCG) in Oral squamous cell carcinoma (OSCC) cases. Materials and Methods This study was conducted on 60 subjects (30 patients with OSCC and 30 subjects served as healthy controls (HCs)). Serum and salivary levels of Synuclein-γ using enzyme linked immunosorbent assay (ELISA) was determined for all participants and the study group was compared versus the healthy control. Results The serum and salivary levels of Synuclein-γ were significantly increased in cases with OSCC than in HCs p-values (

Keywords

Synuclein-γ; OSCC; ELIZA; saliva; serum

How to Cite This Article

Yasser A , Awny S , Hendawy S , Anees M . Assessment of Serum and Salivary levels of Synuclein-γ as a Diagnostic Biomarker in Oral Squamous Cell Carcinoma Patients. Mans J Dent. 2025; 12(2):
Available at: https://doi.org/10.61793/2812-5479.1151

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