Mansoura Journal of Dentistry

Mansoura Journal of Dentistry (MJD) is the official publication of the Faculty of Dentistry – Mansoura University, Egypt. It is is a peer-reviewed journal published quarterly since 2014. The journal uses English as its official language.

Mansoura Journal of Dentistry is honored by the contributions of eminent international editors and reviewers.

Why choose to publish in the Mansoura Journal of Dentistry

  • Emerging journal: The journal follows well-planned steps showing promising progress.

  • Rapid peer review process: The journal adopts a double-blind peer review process. The first decision may take from 3-4 weeks while the final decision may be reached within 6-8 weeks.

  • Rapid peer review process: The journal adopts a double-blind peer review process. The first decision may take from 3-4 weeks while the final decision may be reached within 6-8 weeks.

  • Reasonable article processing charge: The Journal is an open access journal. Authors are kindly requested for article processing charge (APC) for their accepted submissions. There is no submission charge. For APC and payment details, please contact the journal.

Current Issue

Volume 13, Issue 2 (2026)View issue

Current Articles

    • Original Article1 January 2026

      Ultrasound-guided vs Conventional Intraarticular Injection of Hyaluronic Acid for Management of Temporomandibular Joint Internal Derangement: a randomized controlled trial

      Objective: This study aimed to evaluate the clinical efficacy of using ultrasound guidance during intra-articular injection of hyaluronic acid (HA) in the management of patients with TMJ internal derangement. Material/subjects and Methods: Forty patients complaining of anterior disc displacement with reduction (DDwR) not responsive to conservative treatment were enrolled in this study. The diagnosis was based on the current update of diagnostic criteria for temporomandibular disorders (TMDs). Intra-articular injection of Hyaluronic Acid guided by Ultrasound in the first group and Intra-articular Injection (IAI) of HA conventional way in the second group were performed. Articular pain was evaluated using the visual analog scale (VAS). The measured parameters were assessed preoperatively, one week, three month, and six months postoperatively. Data were statistically analyzed (α=0.05). Results: Ultrasound-guided HA injections for the TMJ provide faster pain relief compared to the conventional technique. This method may represent a clinically advantageous approach for optimizing patient outcomes and improving joint function Conclusions: The results of this trial substantiate the integration of ultrasound guidance as a useful adjunct / promising technique for intra-articular TMJ injections. It elevates the procedure from landmark-dependent technique to a targeted and evidence-based intervention. The demonstrated benefits of accelerated pain relief outcomes can significantly enhance patient satisfaction, reduce overall morbidity.
    • Original Article1 January 2026

      Effect of presence of cervical composite restoration on intraoral scanner precision of anterior laminate veneer preparations – an in vitro study

      Objective To evaluate the effect of cervical composite restoration on the precision of digital impressions in anterior laminate veneer preparations. Materials and methods Forty-eight sound human maxillary central incisors were collected and prepared for anterior laminate veneer restorations following standardized preparation protocol. Specimens were grouped into two equal groups according to the presence of cervical composite restoration: With cervical restoration and without cervical restoration. All preparations were scanned 10 times repeatedly using Primescan intraoral scanner and exported as standard tessellation language (STL) files. Precision was evaluated by calculating root mean square (RMS) values through three-dimensional superimposition analysis using Geomagic Control X software. Statistical analysis was performed using student t-test at a significance level of 0.05. Results Veneer preparations without cervical composite restoration demonstrated significantly statistical lower RMS values compared to those with cervical restoration, indicating higher precision. The presence of cervical restoration had statistically significant effect on scan precision (P < 0.001). Conclusions Within the limitations of this in-vitro study, the following can be concluded: Intraoral scanner precision differences are substrate-dependent, cervical composite restorations negatively affect scanning precision of laminate veneer preparations, Primescan has high precision and exhibit single tooth deviations within clinically accepted limits.
    • Original Article1 January 2026

      Fracture resistance of monolithic zirconia restorations after endodontic access cavity preparation: Effect of repair method

      objective: The present study was performed to assess the effect of restoration of access cavity with composite resin filling on fracture resistance of multilayered zirconia crowns. Materials and Methods: Thirty-three sound human mandibular first molars were prepared and restored with three types of monolithic zirconia crowns: High-Translucent Multilayered Plus (HTML), Yttria Multilayered (YML), and Ultra-Translucent Multilayered (UTML) (N=11 each). Standardized access cavities were prepared through the occlusal surfaces, endodontic treatment was completed, and each access opening was repaired using incremental composite resin. The specimens were subjected to thermocycling (10,000 cycles between 5 °C and 55 °C) and cyclic mechanical loading (240,000 cycles at 50 N) prior to single-load fracture testing. Data were statistically analyzed using one-way ANOVA and Tukey post-hoc tests. Results: There was significant interaction (P=.001) of crown material and repair method fracture resistance. High-Translucent Multilayered Plus (HTML) showed the highest fracture value(2132.14±282.86N) followed by Yttria Multilayered (YML) (1665.72±220.98N) and UTML multilayered zirconia (1133.12±150.33N) Conclusions: Both the type of zirconia and the selected repair protocol significantly influence the fracture resistance of monolithic zirconia crowns following endodontic access cavity preparation. High-Translucent Multilayered Plus zirconia demonstrated the greatest overall fracture strength, particularly when repaired with direct composite resin. Ultra-Translucent Multilayered zirconia exhibited the lowest resistance to fracture. These differences highlight the critical role of microstructural composition and yttria concentration in determining the mechanical performance of zirconia restorations after repair.
    • Original Article1 January 2026

      Extended Platelet Rich Fibrin in Lateral Maxillary Sinus Lifting with Simultaneous Implant Placement

      Objective: This study aimed to investigate the influence of extended platelet-rich fibrin (e-PRF) when used in lateral maxillary sinus floor augmentation (MSFA), with particular emphasis on implant stability and peri-implant marginal bone loss. Materials and Methods: Thirteen patients presenting with posterior maxillary tooth loss and a residual bone height of 3–5 mm underwent lateral sinus floor augmentation with concomitant implant placement. A total of 16 implant sites were included and equally allocated into two groups: Group I (n = 8), in which an allograft was applied and covered using a pericardium membrane, and Group II (n = 8), in which e-PRF was used both as the grafting material and as the barrier membrane. Implant stability was assessed immediately after placement and re-evaluated at 6 and 9 months. Marginal bone loss was quantified using cone beam computed tomography (CBCT). Results: Implant stability increased significantly over time in both groups, whereas intergroup comparisons demonstrated no statistically significant differences at any time point (P > 0.05). Likewise, palatal and buccal marginal bone loss did not differ significantly between the two treatment protocols. Conclusions: Lateral sinus lift augmentation with simultaneous implant placement yielded favorable clinical and radiographic outcomes in both groups. The e-PRF approach produced implant stability and marginal bone loss outcomes comparable to those achieved with allograft and a pericardium membrane.
    • Original Article1 January 2026

      Effect of Biodentine and Treated dentine matrix on viability and proliferation of human dental pulp stem cells

      Objective: The present study aimed to assess the dose-dependent effect of Biodentine (BD) and human-treated dentin matrix (hTDM) on the proliferation of human dental pulp stem cells (hDPSCs). Materials and methods: hTDM was prepared and characterized. The concentration of proteins released from BD and hTDM extracts were quantified using the bicinchoninic acid (BCA) assay after 3 and 7 days. hDPSCs were successfully isolated and characterized, then treated with various concentrations of BD extracts (20, 2, and 0.2 mg/mL) and hTDM extracts (100%, 80%, 60%, 40%, 20%, and 10%). Cell viability was determined after 7 days of incubation using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and represented as a percentage relative to untreated control groups. One-way ANOVA statistical analysis followed by post-hoc Tukey test were performed. Results: High-concentration BD (20 mg/mL) significantly reduced hDPSCs viability, indicating cytotoxicity. In contrast, lower BD concentrations (2 and 0.2 mg/mL) slightly enhanced cell proliferation compared with the negative control, with the 0.2 mg/mL exhibiting the most significant enhancement. For hTDM, concentrated extracts (100–40%) significantly decreased cell viability. However, diluted extracts (20% and 10%) preserved high proliferation rates, with no significant differences between them. Conclusions: This study demonstrated the favorable invitro biocompatibility of BD, a commercially available tricalcium silicate cement, and hTDM, an innovative natural biomaterial, on hDPSCs. Lower concentrations, particularly 0.2 mg/mL BD and 10% hTDM, exhibited superior biological outcomes compared with higher doses. Appropriate concentration optimization is essential to maximize regenerative benefits and enable successful clinical translation.
    • Original Article1 January 2026

      Survival Rate and Prognostic Criteria in Oral Squamous Cell Carcinoma Patients: A Retrospective Analysis

      Objective: To evaluate overall survival, disease-free survival (DFS), and associated prognostic factors among patients with oral squamous cell carcinoma (OSCC) treated at a tertiary oncology center in Egypt. Materials/Subjects and Methods: This retrospective cohort study was conducted at the Surgical Oncology Department, Oncology Center, Mansoura University, Egypt. Medical records of patients with histopathologically confirmed primary OSCC diagnosed between January 2011 and December 2021 were reviewed. A total of 140 eligible patients were included. Data collected included demographic characteristics, selected medical history, tumor site, tumor size, TNM stage, histological grade, treatment modality, and follow-up status. Data were entered, managed, and analyzed using SPSS version 22. Survival outcomes were estimated using the Kaplan–Meier method, and univariate comparisons were conducted using the log-rank test. Results: The cohort was predominantly older than 50 years, with a slight male predominance. Oral tongue was the most commonly affected site, followed by buccal mucosa and gingiva. Although T1 tumors represented the largest T category, most patients presented with advanced-stage disease. Kaplan–Meier analysis showed unfavorable long-term survival outcomes for both disease-free and overall survival (OS). Combined oral cavity and neck surgery was significantly accompanied by better DFS, while radiotherapy was accompanied by shorter DFS, likely reflecting its use in higher-risk and more advanced cases. No evaluated variable showed a statistically significant correlation with overall survival in the present univariate analysis. Conclusions: Oral squamous cell carcinoma in this retrospective Mansoura cohort showed unfavorable long-term survival outcomes. Most cases presented with advanced-stage disease, confirming that delayed diagnosis remains a major clinical problem. Combined oral cavity and neck surgery was accompanied by better DFS, underscoring the importance of adequate surgical management. Radiotherapy was accompanied by shorter DFS, most likely because it was used more often in higher-risk and more advanced cases. No evaluated variable demonstrated a statistically significant correlation with overall survival in the present univariate analysis. Overall, prognosis in this cohort appears to be influenced by multiple interacting clinicopathological and treatment-related factors, highlighting the need for earlier detection, standardized pathological documentation, and larger multicenter studies to define more reliable prognostic predictors.
    • Original Article1 January 2026

      An Attempt for in Situ Bio-Root Regeneration by Using Treated Dentin Matrix and Dental Pulp Stem Cells in Albino Rats

      Objectives: This study was conducted to prepare and characterize root-shaped treated dentin matrix (TDM) scaffolds, and to evaluate their efficacy together with seeded dental pulp stem cells (DPSCs) as potential bio-roots in extraction sockets of rat models. Materials and Methods: Root-shaped TDM specimens were prepared and characterized. Following extraction of maxillary incisors, the alveolar sockets were implanted with TDM segments measuring 8 mm in length, either alone (TDM group) or seeded with dental pulp stem cells (TDM/DPSCs group). Animals were euthanized at two and six weeks post-implantation, specimens were processed for histological, histochemical and immunohistochemical analyses. Results: TDM group at 2 weeks showed poor regeneration on the inner and outer surfaces of the implanted scaffolds, while at 6 weeks early connective tissue formation and collagen fiber deposition were observed. TDM/DPSCs group at 2 weeks demonstrated predentin-like tissue formation and preliminary PDL-like tissues, and by 6 weeks exhibited pronounced regenerative outcomes, including dentin-like tissue formation, odontoblast-like cells lining the TDM surface, organized pulp-like tissue, and well-arranged PDL-like collagen fibers at outer surface. Statistical analysis of Masson’s trichrome and Dentin sialophosphoprotienn immunohistochemical staining revealed a statistically significant difference between both groups, with the TDM/DPSCs group showing superior collagen organization and higher odontogenic marker expression in comparison with the TDM group. Conclusion: The TDM/DPSCs construct effectively promotes dentin and periodontal tissue regeneration in rat incisor extraction sockets. This strategy represents a feasible and promising tissue engineering approach for tooth root regeneration and may have potential clinical applications in the treatment of tooth loss.
    • Original Article1 January 2026

      Extended Platelet Rich Fibrin in Mandibular Alveolar Ridge Splitting with Simultaneous Implant Placement

      Purpose: To evaluate, both clinically and radiographically, the use of extended platelet-rich fibrin versus a pericardium membrane in mandibular ridge splitting accompanied by immediate implant placement. Materials and Methods: A total of sixteen implants were placed in eight patients with horizontally atrophic posterior mandibular ridges measuring 3–6 mm in width were randomly assigned to two groups with equal numbers. Both groups underwent ridge splitting with simultaneous implant insertion. In Group I, the intercortical defect was grafted with bone allograft and covered using a pericardium membrane, while Group II received extended platelet-rich fibrin (e-PRF) membrane instead. Clinical assessment focused on assessment of implant stability through resonance frequency analysis and radiographic examination with CBCT was performed to measure alveolar ridge width, bone gain, and bone loss. Results: Immediate postoperative assessment showed that alveolar ridge width increased significantly in both groups. Despite this improvement, there were no statistically significant differences between the two groups regarding implant stability, ridge width measurements, bone gain, or bone resorption (p > 0.05). Conclusion: Extended platelet-rich fibrin provided clinical and radiographic outcomes comparable to a pericardium membrane in mandibular alveolar ridge splitting procedures. e-PRF may be considered a biological alternative for commercially available pericardium membranes.

Most Popular Articles

  • Original Article
    1 September 2022

    Awareness of Evidence Based Recommendations on Toothbrush Bristles Design and Texture among Dentists

    Objective: Dental plaque is a necessary etiologic factor in the onset and progression of dental caries and periodontal disorders. Numerous individual and material-based factors have an impact on dental plaque control. In light of the most recent evidence-based guidelines, this study's purpose is to determine the best toothbrush bristles surface plane design (flat; multilevel; angled), texture (soft; medium; hard) and to estimate how many dentists are aware of that too. Materials and Methods: This is a one-question survey directed on social media platforms of dentists' groups: - “Is it preferable to use a toothbrush with soft or medium bristles, and are toothbrushes with multi-level or angled bristles better than traditional flat bristles for brushing the teeth?”. The answers or reactions were limited to the first valid 400 answers. Results: Comparing the bristles texture (soft & medium) and bristles design (straight & multilevel or angled) showed a statistically significant difference (p ≤ 0.05). Also, there was a statistically significant difference between combining effects taking this descending order soft &multilevel, medium & straight, medium & multilevel and finally soft & straight. Conclusions: Premium toothbrushes based on scientific research with soft, multilevel, or angled bristles were used more frequently by dentists than ones with medium or straight bristles.
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  • Original Article
    1 January 2025

    Digital versus Functional Pick-up Techniques for Two-Implant Retained Mandibular Overdentures: A Crossover Study

    Objective: To evaluate two pick-up techniques—digital and functional—for two-implant retained mandibular overdentures with respect to occlusal force distribution using the digital occlusal analysis system (Occlusense®). Patients and Methods: Twenty completely edentulous, healthy patients were selected from the Prosthodontics Department, Faculty of Dentistry, Mansoura University. Conventional complete dentures were first constructed, followed by placement of two implants in the mandibular canine regions using a guided surgical approach and a delayed loading protocol. For each patient, two sets of digitally fabricated mandibular overdentures were constructed. Patients were randomly assigned into two equal groups: Group I received digital complete overdentures with digitally created spacers for attachment placement, while Group II received digital complete overdentures without spacers. Locator attachments were used to retain the mandibular overdentures to the underlying implant fixture, and housings were incorporated using the direct pickup procedure. Occlusal force distribution was assessed at insertion (T0), after two weeks (T1), and after two months (T2). Results: No significant differences between the groups were observed at T0 and T1 across the anterior, premolar, and molar regions. However, at T2, significant differences were detected between the groups in all regions (p ≤ 0.05). Conclusion: Within the limitations of this study, the digital pick-up technique demonstrated more favorable outcomes, providing a more even distribution of occlusal forces compared to the functional pick-up technique after denture settling
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  • Original Article
    1 June 2023

    Ferrule Effect on Fracture Resistance of Endodontically Treated Teeth Restored With Two Esthetic Post and Core Materials Fabricated With Different Techniques

    Objective: Assessment of ferrule effect on fracture resistance of Customized fiber post and Custom-made PEEK post with a core. Materials and Methods: 28 single-rooted mandibular premolars with approximate similarity in shape and size and no cracks or caries were selected for this study. The length of the root was measured from the root apex to the middle point of the cementoenamel junction in the labial surface; it was about (16±1 mm). Teeth were divided into two groups, each group contained 14 teeth, with a ferrule group and without a ferrule group followed by coronal decapitation of all samples. Endodontic treatment was performed for all samples followed by mounting samples in acrylic blocks and then preparation of post space. Each group of the two groups was subdivided into two subgroups (n=7/subgroup), the first subgroup was restored with custom-made polyether ether ketone (PEEK) post and core, and the second subgroup was restored with customized fiber post and composite resin core. Results: Samples with ferrule (651.68±66.34) had a significantly higher fracture strength value than samples without ferrule (528.86±60.85) (p<0.001). Conclusions: based on the results and conditions of this study, the following findings can be drawn: With ferrule samples are more resistant to fracture than ferrule samples with the two different post types.
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  • Original Article
    1 January 2024

    Biocompatibility Evaluation of EDTA and Chitosan Nanoparticles Gel Forms: In vivo histopathological study

    Objectives: The purpose of this study was to evaluate and compare biocompatibility of gel form chelating agents (EDTA and chitosan NPS) after implantation of polyethylene tubes in rats. Materials and methods: Twenty albino rats were included in this study. Three horizontal incisions were performed on dorsal surface of each rat to receive three polyethylene tubes as subcutaneous implants; two of them filled with tested materials and one empty tube served as control. After 2 and 4 weeks of subcutaneous implantation, 10 rats were sacrificed and implanted polyethylene tubes with surrounding tissues were dissected with 1 cm safety margin. The specimens were submitted to histological preparation and stained with hematoxylin and eosin then investigated using light microscope. The number of inflammatory cells were assessed and statistically compared by One-way analysis of variance (ANOVA), followed by the post hoc Tukey’s test (P.05). After 4 weeks of implantation, the severity of inflammatory cell infiltration was decreased in all groups. Conclusions: All tested materials produced inflammatory reaction. The tissue inflammatory reaction induced by tested materials showed a gradual reduction with time. 0.2% chitosan NPS gel demonstrated superior biocompatibility compared to EDTA gel.
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  • Original Article
    1 March 2022

    Effect of Different Bevel Designs on Microleakage and Shear Bond Strength of Class IV Composite Restoration: A laboratory Study

    Objective: This laboratory study was conducted to evaluate the effect of different bevel designs (2mm bevel, skirt bevel and scalloped bevel) on microleakage and shear bond strength of class IV composite restorations. Materials and Methods: Sixty extracted human permanent maxillary central incisors were selected and a standardized mesio-incisal fracture was created. Teeth were divided into 3 groups (n=20) according to different bevel designs (2mm bevel, skirt bevel and scalloped bevel). All prepared teeth were restored with nano hybrid composite (Filtek Z250, 3M ESPE, St. Paul, MN, USA). Half of specimens were used for microleakage test, specimens were received 3 layers of nail polish, except for a 1 mm around the margins, then immersed in a 0.5% methylene blue dye for 24h. Dye penetration scores were assessed using stereomicroscope. The remaining teeth were utilized for shear bond strength test after measuring the surface area with (Image J) software, specimens were subjected to universal testing machine with crosshead speed of 1 mm/min. Results: Regarding microleakage, the result of Chi-Square test revealed that there was no significant difference between different bevel designs (p>0.05). Regarding shear bond strength the results of one-way ANOVA revealed the highest mean value for the 2mm bevel (16.74±5.29Mpa), while the lowest mean value recorded for the skirt bevel (12.20±1.54Mpa). Conclusion: Bevels can be advantageous in reducing microleakage and increasing shear bond strength in class IV restoration. However, the higher shear bond strength and minimum microleakage can be obtained with 2mm bevel, and it can be recommended for cliniciansn.
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  • Original Article
    1 September 2022

    Evaluation of The Effects of The Incisal Capping Twin Block on The Flaring of The Lower Incisors in The Treatment of Skeletal Class II Malocclusion

    Objective: The purpose of this research was to evaluate the effect of the incisal capped Twin Block on the proclination of the lower incisors in the treatment of skeletal class II malocclusion. Materials and Methods: Ten patients (age ranged from 9 to 14 y) with skeletal class II due to mandibular retrusion were selected and treated with the incisal capped Twin Block appliance. Overjet was more than 4 mm. Lateral cephalometric radiographs, photographs, and study casts were obtained before and after treatment. The collected data were analyzed using (SPSS) program for Windows (Standard version 26). The treatment duration was about 8-12 months. Results: Incisal capped TB appliance had Dento-skeletal and soft tissue effects including non-significant effect on the maxillary growth, significant advancement of the mandible, increase in the posterior and total anterior facial height, decrease in the overjet and overbite, retroclination of the upper incisors, significant proclination of the lower incisors and improvement of the soft tissue profile. Conclusions: The incisal capped Twin Block appliance was effective in the correction of skeletal class II patients. It produced a combination of skeletal and dental effects by forward movement of the mandible, palatal tipping of the upper incisors and labial flaring of the lower incisors. The addition of the acrylic capping to the lower incisors did not control the position of the lower teeth and did not prevent their labial flaring.
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