Immunohistochemical Assessment of Ki-67 in Oral Lichen Planus

Ibrahem Gamal, Department of Oral Pathology, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.Follow
Mahmoud Fathy El-Sherbeny, Post Graduate Master Student, Department of Oral Pathology, Faculty of Dentistry, Mansoura University and Horus University, Egypt.
Sherif Yousef El Nagdy, Professor, Department of oral pathology, Faculty of Dentistry, Mansoura University and Horus University, Egypt.
Nadia Abbas Ibrahim El-sissy, Professor, Department of oral pathology, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.

Article Type

Original Article

Section/Category

Oral Pathology

Abstract

Objective: The purpose of the current study was to assess cell proliferation by analyzing the expression of Ki-67 in 30 cases of oral lichen planus (OLP). Material and methods: 30 archival paraffin blocks of OLP were examined for Ki-67 expression using immunohistochemical staining. Normal oral mucosa served as a control. After carefully examining the tissue samples, the number of positive cells was counted in order to semi-quantitatively characterize the expression pattern. Scores ranging from 1 to 3 were assigned to nuclear immunostaining for Ki-67 proliferation. SPSS-13 program was used for the statistical analysis, and p

Keywords

Oral lichen planus (OLP), Oral epithelial dysplasia(OED), orally potential malignant disorders (OPMD)

How to Cite This Article

Gamal I , El-Sherbeny M , Nagdy S , El-sissy N . Immunohistochemical Assessment of Ki-67 in Oral Lichen Planus. Mans J Dent. 2025; 12(2):
Available at: https://doi.org/10.61793/2812-5479.1150