To evaluate the adjunctive application of human placental extracts (placentrex gel) on the healing of gingival tissue after gingivectomy.
Materials and methods
The present study was made on twenty patients who were suffering from gingival enlargement and seeking for gingivectomy procedures. Ten patients were treated with gingivectomy with application of placentrex gel after surgery for a month as study group. The other ten patients were treated with gingivectomy without the application of placentrex gel after surgery as control group. Different clinical periodontal parameters were recorded including the scores of Plaque index, Postoperative pain index, Wound-Healing index and Degree of keratinization postoperatively. These clinical periodontal parameters were recorded at day 10 (T1), day 20 (T2) and day 30 (T3) for all patients for evaluation of gingival healing after application of placentrex gel.
It was found that gingivectomy in combination with the use of a gel containing human placental extracts (Placentrex gel) in group I (study) demonstrated a significant acceleration in the gingival healing rate, reepithelilization degree and further reduction in pain sensation were observed when compared to the results of group II (control) after gingivectomy alone. Based on the results of the clinical periodontal parameters that were recorded, the results of this study showed the mean of postoperative pain index (VAS) at (T3) of group I was 0±0 and for group II was 1.2±1.09 (P=0.0023**), Wound-Healing index mean scores at (T3) of the group I was 4±0 and for group II was 2.8± 0.44 (P
Adjunctive application of human placental extracts (Placentrex gel) represents an accelerated healing product as an adjunct to gingivectomy by acceleration of reepithelization rate of gingival tissue.
gingival enlargement, gingivectomy, placentrex gel
How to Cite This Article
Ashmawy R , Elkashty A , Shennawi M .
Clinical evaluation of gingival healing following gingivectomy with application of human placental extracts (placentrex gel).
Mans J Dent.
Available at: https://doi.org/10.61793/2812-5479.1010
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